Abstract Background Patients with metabolic syndrome, who are characterized by co-existence of insulin resistance, hypertension, hyperlipidemia, and obesity, are also prone to develop non-alcoholic fatty liver disease (NAFLD).Although the prevalence and severity of NAFLD is significantly greater in men than women, the mechanisms by which gender mod
The thymus plays a fundamental role in establishing and maintaining central and peripheral tolerance and defects in thymic architecture or AIRE expression result in the development of autoreactive lymphocytes.Patients with partial DiGeorge Syndrome (pDGS) and Down Syndrome (DS) present alterations in size and architecture of the thymus and higher r
Rice, the first crop to be fully sequenced and annotated in the mid-2000s, is an excellent model species for crop research due mainly to its relatively small genome and rich genetic diversity.The 130-million-year-old cereal came into the limelight in the 1960s when the semi-dwarfing gene sd-1, better known as the Pipes “green revolution”
Hemorrhagic fever with renal syndrome (HFRS) is an emerging infectious disease that remains a global public health threat.The highest incidence rate is among zoonotic disease cases in Russia.Most cases of HFRS are reported in the Volga region of Russia, Canvas Wall Art 3 which commonly identifies the Puumala virus (PUUV) as a pathogen.HFRS manageme
ObjectiveProblematic drinking is highly prevalent among the general population, oftentimes leading to significant negative consequences, including physical injury, psychological problems and financial hardship.In order to design targeted early interventions for problematic drinking, it is important to understand the mechanisms that render individua